Solve puzzles to advance research using RNAs
Eterna invites everyone to design the tiny molecules found in the heart of every cell.
Play Now About Eterna
How It Works
Solve Puzzles
Players solve RNA design puzzles which address research problems.
Test
Scientists test player solutions in real wet-lab experiments.
Analyze
Both players and experts use data from experiments to improve their designs and build new tools.
Solve Puzzles
Players solve RNA design puzzles which address research problems.
Test
Scientists test player solutions in real wet-lab experiments.
Analyze
Both players and experts use data from experiments to improve their designs and build new tools.
Solve Puzzles
Players solve RNA design puzzles which address research problems.
Test
Scientists test player solutions in real wet-lab experiments.
Analyze
Both players and experts use data from experiments to improve their designs and build new tools.
Our Impact
Technology
Players and researchers have created design tools, predictive AI models, large data sets, and DNA template libraries. All technologies are freely available for non-commercial use, and commercial licenses support Eterna's ongoing research.
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Publications
Eterna players have contributed to over 30 scientific publications, including as lead authors, in journals such as Nature Communications, PLOS Computational Biology, and Proceedings of the National Academy of Sciences.
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OpenVaccine
During the pandemic, the Eterna community created and published designs for a more stable mRNA vaccine for COVID-19 optimized for new variants. Eterna's open challenges address several important areas of RNA medicine.
Learn moreFeatured Lab Challenge
OpenKnot
Many important biological processes depend on RNAs that form pseudoknots, and they are among the most conserved structures in evolutionary history. However, scientists still have much to learn about their properties, structure, and functions.
Enter lab
